漠宝生物科技

Make Research Easy

服务热线:0592-5771844

产品中心

PRODUCTS CENTER

当前位置:首页产品中心免疫学内毒素检测和去除L00402ToxinEraser™ Endotoxin Removal Resin

ToxinEraser™ Endotoxin Removal Resin
产品简介:

ToxinEraser™ Endotoxin Removal Resin utilizes immobilized polymixin B to bind and remove pyrogens from solution.

产品型号:L00402

更新时间:2025-07-22

厂商性质:代理商

访 问 量 :92

服务热线

0592-5771844

立即咨询
产品介绍

The ToxinEraser™ Endotoxin Removal Resin utilizes immobilized polymixin B to bind and remove pyrogens from solution. The polymixins are a family of antibiotics that contain a cationic cyclopeptide with a fatty acid chain. Polymixin B neutralizes the biological activity of endotoxins by binding to the lipid A portion of bacterial lipopolysaccharide.


Description

Lipopolysaccharide (LPS) is a bacterial endotoxin, and a major constituent of the cell walls of gram-negative bacteria. During gram-negative bacteremia or endotoxemia, LPS is the principal pathophysiological mediator by which bacteria can cause hypotension, organ failure, disseminated intravascular coagulation, and fatal shock in mammalian hosts. The removal of these endotoxins is highly necessary for downstream processes.

The ToxinEraser™ Endotoxin Removal Resin utilizes immobilized polymixin B to bind and remove pyrogens from solution. The polymixins are a family of antibiotics that contain a cationic cyclopeptide with a fatty acid chain. Polymixin B neutralizes the biological activity of endotoxins by binding to the lipid A portion of bacterial lipopolysaccharide. 


产品概述

Product Information

Binding Capacity: Up to 2,000,000 EU/ml resin. 

Ligand: Modified PMB (Polymixin B)

 pH Stability: pH 5 -10 

Support Matrix :4% cross-linked agarose, spherical beads 

Mean Particle Size :90 μm 

Types of substances that can be applied to the column :Protein, including peptides and antibody, polysaccharide, etc. 

Applicable Ionic Strength :0.1 to 0.5 M NaCl 

Substances tested that do not interfere with performance: 20% DMSO, 20% ethanol, 20% glycerol; 1 M urea, 300 mM imidazole; 0.05% Tween 20, 10 mM DTT, etc.


Key Features

High stability and high removal efficiency.

High binding capacity: > 2, 000, 000 EU / ml (CV).

Reusable up to five times if properly regenerated.


产品属性

Storage & Stability :2°C to 8°C (Do not freeze.) 


在线留言

ONLINE MESSAGE

留言框

  • 产品:

  • 您的单位:

  • 您的姓名:

  • 联系电话:

  • 常用邮箱:

  • 省份:

  • 详细地址:

  • 补充说明:

  • 验证码:

    请输入计算结果(填写阿拉伯数字),如:三加四=7
  • 服务热线 0592-5771844
  • 电子邮箱

    63706983@qq.com

关注公众号

Copyright © 2025 漠宝(厦门)生物科技有限公司版权所有    备案号:闽ICP备2021000608号-1

技术支持:化工仪器网    sitemap.xml